By Stanley T. Crooke,Archie W. Prestayko
Part I is a basic evaluate of anti-cancer medicinal drugs as regards their motion mechanisms, pharmacokinetics, pharmacology, identified toxicities, and scientific application. those medications comprise alkylating brokers equivalent to mitomycin C and nitrosoureas; plant alkaloids comparable to maytansine; antibiotics equivalent to anthracyclines; platinum-containing complexes; antimetabolites; and hormones. half II examines the molecular pharmacology of a few significant drug periods, particularly, bleomycin and anthracycline. The textual content additionally discusses the chemistry, mechanism, and any structure-activity relationships present in those drug periods. half III discusses intimately the medical pharmacology of a few antitumor medications, for instance, cisplatin and nitrosoureas. The textual content comprises the scientific purposes, biochemistry, metabolism, and using mathematical versions in examining or describing ensuing info.
The publication is useful for pharmacologists, molecular biologists, and scientists enthusiastic about cancer-research.
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Antineoplastic Agents: Antineoplastic Agents v. 3 by Stanley T. Crooke,Archie W. Prestayko